Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GMNN | O75496 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615547 | 0.95 | LMNA (0.52) | MAPK1TSHRMAPTGMNNLMNA | |
| SCHEMBL11612500 | 0.92 | FFAR4 (0.49) | MAPK1TSHRMAPTGMNNLMNA | |
| SCHEMBL28047150 | 0.90 | FFAR4 (0.59) | MAPK1TSHRMAPTGMNNLMNA | |
| SCHEMBL11666011 | 0.89 | FFAR4 (0.51) | TSHRMAPTMEN1KMT2AFFAR4 | |
| SCHEMBL11613557 | 0.89 | FFAR4 (0.51) | TSHRMAPTMEN1KMT2AFFAR4 | |
| SCHEMBL11745383 | 0.88 | FFAR4 (0.48) | MAPK1TSHRMAPTGMNNLMNA | |
| SCHEMBL23288460 | 0.87 | MAPK1 (0.58) | MAPK1TSHRMAPTGMNNLMNA | |
| SCHEMBL23565739 | 0.85 | MAPK1 (0.64) | MAPK1TSHRMAPTGMNNLMNA | |
| SCHEMBL11107510 | 0.85 | MAPK1 (0.64) | MAPK1TSHRMAPTGMNNLMNA | |
| SCHEMBL23288413 | 0.85 | MAPK1 (0.64) | MAPK1TSHRMAPTGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097504-A | 11,12-Secoprostaglandins | MERCK & CO., INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4092356-A | 11,12-Secoprostaglandins | MERCK & CO., INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4066692-A | 11,12-SECOPROSTAGLANDINS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |