Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613594 | 1.00 | ALOX15 (0.61) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL11744229 | 1.00 | ALOX15 (0.61) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL9609504 | 1.00 | ALOX15 (0.61) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL14549209 | 0.88 | ALOX15 (0.52) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL1784119 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL1784117 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL10048651 | 0.86 | ALOX15 (0.64) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL12654601 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL1783447 | 0.83 | ALOX15 (0.41) | ALOX15ALDH1A1TSHRUSP2 | |
| SCHEMBL1783445 | 0.83 | ALOX15 (0.41) | ALOX15ALDH1A1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123465-A | SELECTIVE HYDROGENATION CATALYSTS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-31 | — | — | US | disclosed |
| US-4115417-A | ENANTIOSELECTIVITY | HOFFMANN-LA ROCHE INC. (US) | 1978-09-19 | — | — | US | disclosed |