Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617614 | 1.00 | OPRL1 (0.49) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11475502 | 0.95 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11475849 | 0.95 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11475501 | 0.95 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL17072238 | 0.89 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL9013291 | 0.88 | OPRL1 (0.41) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL8452166 | 0.86 | OPRL1 (0.49) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL8452168 | 0.86 | OPRL1 (0.49) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL8100549 | 0.84 | OPRM1 (0.41) | OPRL1OPRM1OPRK1OPRD1CHRM4 | |
| SCHEMBL10906004 | 0.84 | OPRL1 (0.39) | OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130502-A | Liquid crystalline cyclohexane derivatives | MERCK PATENT GESELLSCHAFT MIT (DE) | 1978-12-19 | — | — | US | disclosed |