Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617121 | 0.92 | PTGDR2 (0.40) | PTGDR2SMN1; SMN2TP53GAALMNA | |
| SCHEMBL11615839 | 0.86 | PTGDR2 (0.47) | PTGDR2SMN1; SMN2TP53GAAHTT | |
| SCHEMBL11616625 | 0.84 | PTGDR2 (0.41) | PTGDR2NPSR1PPARG | |
| SCHEMBL11618315 | 0.84 | PTGDR2 (0.48) | PTGDR2SMN1; SMN2TP53GAAHTT | |
| SCHEMBL11618584 | 0.83 | RAB9A (0.42) | PTGDR2SMN1; SMN2TP53GAAHTT | |
| SCHEMBL11616149 | 0.80 | TP53 (0.42) | PTGDR2SMN1; SMN2TP53GAAHTT | |
| SCHEMBL11036231 | 0.79 | PTGDR2 (0.44) | PTGDR2SMN1; SMN2TP53GAAHTT | |
| SCHEMBL11618741 | 0.78 | PTGDR2 (0.42) | PTGDR2SMN1; SMN2TP53GAAHTT | |
| SCHEMBL11610569 | 0.77 | PTGDR2 (0.47) | PTGDR2SMN1; SMN2TP53GAAPOLB | |
| SCHEMBL11615866 | 0.77 | PTGDR2 (0.45) | PTGDR2SMN1; SMN2TP53GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |