Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | EP300 | Q09472 | 1/20 | 0.62 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881664 | 0.78 | IDO1 (0.76) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL485125 | 0.78 | IDO1 (0.76) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL331453 | 0.78 | IDO1 (1.00) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL1193308 | 0.78 | KMT2A (0.52) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL11808700 | 0.77 | IDO1 (0.54) | IDO1EP300KAT8ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL6155452 | 0.77 | EP300 (1.00) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL9067745 | 0.75 | IDO1 (0.48) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL1892202 | 0.74 | ALDH1A1 (0.67) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL5746648 | 0.73 | IDO1 (0.57) | IDO1EP300KAT8ALDH1A1TDP1 | |
| SCHEMBL18499935 | 0.73 | KMT2A (0.68) | IDO1ALDH1A1KMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097450-A | REPAIRING NARROW CREVICE IN NICKEL-BASE SUPERALLOY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-3935226-A | Substituted phenanthroline pigments | ALLIED CHEMICAL CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |