Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 9/20 | 0.61 |
| ▸ | DHFR | P00374 | 8/20 | 0.61 |
| ▸ | F2R | P25116 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232592 | 0.93 | SLC2A1 (0.64) | SLC2A1DHFRF2R | |
| SCHEMBL11617981 | 0.86 | SLC2A1 (0.62) | SLC2A1DHFRF2R | |
| SCHEMBL24166658 | 0.85 | DHFR (0.55) | SLC2A1DHFRF2R | |
| SCHEMBL25074353 | 0.85 | DHFR (0.65) | SLC2A1DHFRF2R | |
| SCHEMBL30252143 | 0.85 | DHFR (0.65) | SLC2A1DHFRF2R | |
| SCHEMBL29232537 | 0.82 | DHFR (0.54) | SLC2A1DHFR | |
| SCHEMBL11614277 | 0.76 | SLC2A1 (1.00) | SLC2A1DHFRF2R | |
| SCHEMBL29232451 | 0.76 | DHFR (0.49) | SLC2A1DHFR | |
| SCHEMBL9568517 | 0.74 | DHFR (1.00) | SLC2A1DHFR | |
| SCHEMBL9543453 | 0.73 | DHFR (1.00) | SLC2A1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118561-A | ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |