Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.56 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11618683 | 0.84 | PTGDR2 (0.51) | PTGDR2SCN4ASLC6A9PTGER1TBXA2R | |
| SCHEMBL11646426 | 0.79 | PTGDR2 (0.54) | PTGDR2SCN4ASLC6A9PTGER1TBXA2R | |
| SCHEMBL11619688 | 0.77 | PTGDR2 (0.63) | PTGDR2SLC6A9PTGER1C5AR1CYP2C9 | |
| SCHEMBL11646275 | 0.77 | PTGDR2 (0.55) | PTGDR2SCN4ASLC6A9PTGER1TBXA2R | |
| SCHEMBL16150998 | 0.75 | PTGDR2 (0.53) | PTGDR2SLC6A9 | |
| SCHEMBL11617344 | 0.74 | PTGDR2 (0.52) | PTGDR2SLC6A9PTGER1ADRB2ADRB1 | |
| SCHEMBL2067287 | 0.74 | PTGDR2 (0.51) | PTGDR2SCN4ASLC6A9PTGER1PPARG | |
| Bromide SCHEMBL11619657 | 0.73 | PTGDR2 (0.51) | PTGDR2SLC6A9PTGER1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11616171 | 0.73 | ALDH1A1 (0.58) | PTGDR2SLC6A9CYP2C9ADRB2CYP2D6 | |
| SCHEMBL3759371 | 0.73 | PTGDR2 (0.57) | PTGDR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4074998-A | USING A SUBSTITUTED PHENOXYALKYLAMINE OR PHENYLTHIOALKYLAMINE | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |