Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329722 | 0.79 | SLC6A4 (0.63) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11620352 | 0.78 | SLC6A4 (0.53) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18688367 | 0.76 | MEN1 (0.85) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14266763 | 0.76 | SLC6A4 (0.53) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13123436 | 0.74 | MEN1 (0.52) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9843937 | 0.74 | SLC6A4 (0.56) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2776498 | 0.73 | IDO1 (0.56) | MEN1KMT2ACYP1A2CYP3A4RAB9A | |
| SCHEMBL11620169 | 0.73 | IDO1 (0.56) | MEN1KMT2ACYP3A4MAPTCA2 | |
| SCHEMBL2092148 | 0.73 | SLC6A4 (0.61) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10875650 | 0.72 | GAA (0.54) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232070-A | Quinolinone alkaloid derivative containing acylhydrazone group on 1-site nitrogen atom and preparation method and application thereof | 太原理工大学 | 2022-10-25 | — | — | CN | disclosed |
| US-4076943-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-28 | — | — | US | disclosed |
| US-4061653-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |
| US-3950528-A | HYPOTENSIVE AGENTS, SALURETICS, DIURETICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |