Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.85 |
| ▸ | MAPT | P10636 | 6/20 | 0.85 |
| ▸ | RAB9A | P51151 | 5/20 | 0.85 |
| ▸ | NPC1 | O15118 | 4/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.82 |
| ▸ | RECQL | P46063 | 1/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779007 | 0.91 | MEN1 (0.72) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL5923871 | 0.91 | MEN1 (0.72) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL5605002 | 0.90 | MEN1 (0.86) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL856271 | 0.88 | RAB9A (0.71) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL5923861 | 0.85 | MAPT (0.64) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11887733 | 0.83 | CA1 (0.70) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL4343902 | 0.79 | MAPT (0.60) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL4347198 | 0.79 | MEN1 (0.63) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL4349895 | 0.77 | MEN1 (0.57) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL4349832 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017050990-A1 | 1,4-DI-(4-METHYLTHIOPHENYL)-3-PHTALOYLAZETIDINE-2-ONE AND THE DERIVATIVES THEREOF | UNIVERSITE DE NANTES (FR) | 2017-03-30 | — | — | WO | disclosed |