SCHEMBL11619720

SCHEMBL11619720

COc1cccc(C(C)C(C)c2cccc(OC)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CASR P41180 3/20 0.53
ACHE P22303 1/20 0.52
AOC3 Q16853 3/20 0.51
TAAR1 Q96RJ0 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23544819 0.94 CASR (0.57) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL11991411 0.91 AOC3 (0.51) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL11991412 0.91 AOC3 (0.51) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL23745686 0.91 AOC3 (0.51) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL14284906 0.91 AOC3 (0.51) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL24925808 0.88 AOC3 (0.54) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL21286867 0.88 AOC3 (0.54) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL18793772 0.88 AOC3 (0.54) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL10290007 0.86 CASR (0.53) CASRACHEAOC3TAAR1L3MBTL1
SCHEMBL84440 0.86 HDAC4 (0.55) CASRACHEAOC3TAAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4094994-A ANTICANCER AGENTS, TUMOR INHIBITION, HORMONE-DEPENDENT CARCINOMAS KLINGE PHARMA GMBH (DT) 1978-06-13 US disclosed