Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919682 | 0.93 | PTPN1 (0.56) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E | |
| SCHEMBL212382 | 0.92 | RAB9A (0.68) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E | |
| SCHEMBL3101558 | 0.91 | PTPN1 (0.64) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E | |
| SCHEMBL3611504 | 0.91 | PTPN1 (0.57) | PTPN1SMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL8880032 | 0.91 | HCAR2 (0.55) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E | |
| Hydrochloric Acid SCHEMBL8880218 | 0.90 | RAB9A (0.66) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E | |
| SCHEMBL7999942 | 0.89 | PTPN1 (0.50) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E | |
| Hydrochloric Acid SCHEMBL8878911 | 0.89 | HCAR2 (0.53) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E | |
| Hydrochloric Acid SCHEMBL6822320 | 0.89 | PTPN1 (0.56) | PTPN1SMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL3533246 | 0.89 | SMN1; SMN2 (0.51) | PTPN1SMN1; SMN2RAB9AHCAR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159336-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |