Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Emorfazone SCHEMBL26203 | 0.78 | BRD4 (0.46) | ALDH1A1GAABRD4BRD9ITGB1 | |
| Fepradinol SCHEMBL151235 | 0.68 | KDM4E (0.55) | ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| Fepradinol SCHEMBL29454386 | 0.67 | KDM4E (0.53) | ALDH1A1L3MBTL1LMNA | |
| Fepradinol SCHEMBL1649187 | 0.66 | KDM4E (0.52) | ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| Metamizole SCHEMBL5644145 | 0.65 | KDM4E (0.60) | ALDH1A1BRD4BRD9SMN1; SMN2PTGS1 | |
| SCHEMBL22001230 | 0.58 | KDM4E (0.52) | ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL18394752 | 0.58 | L3MBTL1 (0.52) | ALDH1A1SMN1; SMN2L3MBTL1LMNAHSD17B10 | |
| SCHEMBL2555460 | 0.57 | BRD4 (0.46) | ALDH1A1GAABRD4BRD9ITGB1 | |
| SCHEMBL10784774 | 0.57 | ADRB3 (0.47) | ALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL18412809 | 0.57 | KMT2A (0.48) | ALDH1A1BRD4BRD9SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017294-A1 | HUMAN ANTI-RANKL ANTIBODIES | SCHERING CORPORATION (US) | 2011-02-10 | — | — | WO | disclosed |