Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | CTSG | P08311 | 1/20 | 0.57 |
| ▸ | CMA1 | P23946 | 1/20 | 0.57 |
| ▸ | CTRC | Q99895 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 4/20 | 0.55 |
| ▸ | GSK3B | P49841 | 4/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40679 | 0.82 | POLB (0.61) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL290791 | 0.81 | POLB (0.70) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL7131427 | 0.81 | ELANE (0.53) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL5011821 | 0.78 | GSK3A (0.53) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL5963434 | 0.77 | L3MBTL1 (0.49) | ELANEF2PLGCTSGCMA1 | |
| Bicarbonate SCHEMBL25171118 | 0.76 | POLB (0.64) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL10559302 | 0.76 | GSK3A (0.70) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL18669202 | 0.76 | POLB (0.54) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1553262 | 0.74 | L3MBTL1 (0.54) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL5448612 | 0.73 | KMT2A (0.80) | ELANEF2PLGCTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130711-A | DEHYDROGENATION OF A N-HYDROXYALKYL N-AMIDOALKYL AMINE, REDUCED COPPER CATALYST | THE DOW CHEMICAL COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4082748-A | CATALYTIC DEHYDROCYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1978-04-04 | — | — | US | disclosed |