Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710847 | 0.82 | MAPK1 (0.62) | MAPK1ALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL13631407 | 0.77 | MAPK1 (0.72) | MAPK1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL7764225 | 0.76 | MAPK1 (0.36) | MAPK1ALDH1A1HPGDCYP1A2KDM4C | |
| SCHEMBL20518663 | 0.76 | MAPK1 (1.00) | MAPK1ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL18839784 | 0.76 | MAPK1 (0.56) | MAPK1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL12843973 | 0.73 | MAPK1 (0.66) | MAPK1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL10911332 | 0.72 | MAPK1 (0.51) | MAPK1LMNAKMT2ACYP1A2P2RX7 | |
| SCHEMBL95236 | 0.69 | — | — | |
| SCHEMBL10968077 | 0.68 | KDM4E (0.50) | MAPK1ALDH1A1LMNAHPGDHSD11B1 | |
| SCHEMBL11675781 | 0.67 | MAPK1 (0.46) | MAPK1ALDH1A1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | claimed |