Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162027 | 1.00 | NR3C1 (0.40) | NR3C1PGRNR3C2AR | |
| SCHEMBL1162086 | 0.90 | NR3C1 (0.48) | NR3C1PGRNR3C2AR | |
| SCHEMBL1161871 | 0.83 | NR3C1 (0.57) | NR3C1PGRNR3C2AR | |
| SCHEMBL1161890 | 0.79 | NR3C1 (0.51) | NR3C1PGRNR3C2AR | |
| SCHEMBL1161375 | 0.79 | NR3C1 (0.59) | NR3C1PGRNR3C2AR | |
| SCHEMBL1161883 | 0.79 | NR3C1 (0.61) | NR3C1PGRNR3C2AR | |
| SCHEMBL12015530 | 0.78 | NR3C1 (0.48) | NR3C1PGRNR3C2AR | |
| SCHEMBL3969761 | 0.76 | NR3C1 (0.69) | NR3C1PGRNR3C2AR | |
| SCHEMBL1161783 | 0.75 | NR3C1 (0.51) | NR3C1PGRNR3C2AR | |
| SCHEMBL1161667 | 0.74 | NR3C1 (0.45) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459524-A2 | NOVEL COMPOUNDS AS MODULATORS OF GLUCOCORTICOID RECEPTORS | Cadila Healthcare Limited (IN) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011016050-A2 | NOVEL COMPOUNDS AS MODULATORS OF GLUCOCORTICOID RECEPTORS | CADILA HEALTHCARE LIMITED (IN) | 2011-02-10 | — | — | WO | disclosed |