Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774935 | 0.80 | IKBKB (0.42) | MEN1KMT2AMAPTNR1I2LMNA | |
| SCHEMBL17774966 | 0.79 | S100B (0.56) | MEN1KMT2AMAPTLMNACYP3A4 | |
| SCHEMBL17779281 | 0.79 | MAPT (0.47) | MEN1KMT2AMAPTNR1I2LMNA | |
| SCHEMBL17774952 | 0.77 | S100B (0.46) | MEN1KMT2AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL17774956 | 0.76 | IKBKB (0.41) | MEN1KMT2AMAPTNR1I2LMNA | |
| SCHEMBL17774973 | 0.75 | IKBKB (0.39) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL17779227 | 0.74 | IKBKB (0.38) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL17774929 | 0.73 | S100B (0.45) | MEN1KMT2AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL17774926 | 0.73 | MAPT (0.36) | MEN1KMT2AMAPTNR1I2LMNA | |
| SCHEMBL17774938 | 0.72 | IKBKB (0.39) | MEN1KMT2AMAPTNR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |