Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973211 | 0.81 | CYP3A4 (0.42) | MEN1KMT2ACYP3A4HMGCR | |
| SCHEMBL9124125 | 0.79 | CYP3A4 (0.40) | MEN1KMT2ACYP3A4 | |
| SCHEMBL7011851 | 0.79 | CYP3A4 (0.40) | MEN1KMT2ACYP3A4 | |
| SCHEMBL5908938 | 0.77 | CYP3A4 (0.46) | MEN1KMT2ACYP3A4HMGCR | |
| SCHEMBL3815405 | 0.77 | CYP3A4 (0.46) | MEN1KMT2ACYP3A4HMGCR | |
| SCHEMBL4981966 | 0.75 | — | — | |
| SCHEMBL23236814 | 0.75 | — | — | |
| SCHEMBL3820534 | 0.74 | LPAR3 (0.38) | MEN1KMT2ACYP3A4HMGCR | |
| SCHEMBL483169 | 0.71 | — | — | |
| SCHEMBL11735580 | 0.69 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097593-A | O-Alkyl-S- 1,6-dihydro-6-thioxo-pyridazin-(1)-yl methyl!-(thiono)-(di)-thiol-phosphoric (phosphonic) acid esters and ester-amides and nematicidal, insecticidal and acaricidal compositions thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |