Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806490 | 0.81 | PDE4A (0.40) | MGAMPDE4ATSHRPGDSLC6A3 | |
| SCHEMBL3841888 | 0.74 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL333118 | 0.72 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21904376 | 0.72 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21904277 | 0.72 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| Cadaverine Tartrate SCHEMBL27616108 | 0.71 | MGAM (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10837934 | 0.71 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7952614 | 0.71 | PDE4A (0.38) | PDE4ATSHRPGDKMT2AOR51E2 | |
| SCHEMBL8224464 | 0.70 | MGAM (0.41) | MGAMALDH1A1TSHRKMT2A | |
| SCHEMBL2168980 | 0.70 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103023-A | ANTIULCER, 3,3A,6,6A-TETRAHYDROFURO(3,4-B)FURAN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-07-25 | — | — | US | disclosed |