Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12987705 | 0.81 | CES2 (0.44) | KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL11513135 | 0.79 | PDE4A (0.40) | TSHR | |
| SCHEMBL9806490 | 0.79 | PDE4A (0.40) | MGAMTP53TSHR | |
| SCHEMBL29169801 | 0.78 | USP2 (0.50) | MGAMUSP2ALDH1A1CNR1CNR2 | |
| SCHEMBL29169842 | 0.77 | USP2 (0.50) | MGAMUSP2ALDH1A1CNR1CNR2 | |
| SCHEMBL11150083 | 0.77 | GPR84 (0.50) | GPR84FFAR1PLA2G4BTP53TSHR | |
| SCHEMBL3345590 | 0.77 | GPR84 (0.50) | GPR84FFAR1PLA2G4BTP53TSHR | |
| SCHEMBL6120610 | 0.76 | GPR84 (0.46) | GPR84FFAR1PLA2G4BTP53TSHR | |
| SCHEMBL7773504 | 0.76 | GPR84 (0.46) | GPR84FFAR1PLA2G4BTP53TSHR | |
| SCHEMBL27681636 | 0.76 | GPR84 (0.46) | GPR84FFAR1PLA2G4BTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079798-C | 3 -aryl -tetronic acid derivatives, the production thereof and the use thereof as anti-parasitic agents | BAYER AG (DE) | 2002-02-27 | — | — | CN | disclosed |
| US-6051723-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-18 | — | — | US | disclosed |
| US-6051723-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-18 | — | — | US | disclosed |
| US-5830825-A | INSECTICIDES, HERBICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| US-5830825-A | INSECTICIDES, HERBICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| CN-1175257-A | 3-aryl-tetronic acid derivatives, their production and use as pesticides | BAYER AG (DE) | 1998-03-04 | — | — | CN | disclosed |