Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624596 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL11196673 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTFBP1KDM4E | |
| SCHEMBL11620809 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10583556 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL11625707 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2APOLBNPC1RAB9A | |
| SCHEMBL11227836 | 0.77 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL11622914 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10800024 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KMT2ATSHRPOLBNPC1 | |
| SCHEMBL11781396 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBGAA | |
| SCHEMBL11623297 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29669-E | CYCLIZATION OF GLYCINEAMIDES | PFIZER, INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-RE29668-E | 4-OXO-1,2-BENZOTHIAZINE-3-CARBOXAMIDE, 1,1-DIOXIDES, ANTIINFLAMMATORY | PFIZER INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-3971802-A | ANTIINFLAMMATORY | PFIZER INC. (US) | 1976-07-27 | — | — | US | disclosed |
| US-3954786-A | ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |