Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | TACR2 | P21452 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799802 | 0.84 | HTR2A (0.50) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL11626763 | 0.84 | HTR2A (0.50) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL21799659 | 0.84 | HTR2A (0.50) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL21799652 | 0.84 | HTR2A (0.50) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL21799549 | 0.84 | HTR2A (0.50) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL21799658 | 0.84 | HTR2A (0.50) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL21799711 | 0.84 | HTR2A (0.50) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL11630630 | 0.83 | SLC2A1 (0.44) | SLC2A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL21799476 | 0.82 | HTR2A (0.47) | SLC2A1ALDH1A1SIGMAR1TAAR1 | |
| SCHEMBL21799461 | 0.77 | ALDH1A1 (0.53) | SLC2A1LMNAALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088771-A | 1-Lower alkyl-4,5-dihydro-5-phenyl-2-lower alkoxy carbonylaminoimidazoles and substituted phenyl derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1978-05-09 | — | — | US | disclosed |