SCHEMBL11623754

SCHEMBL11623754

O=[N+]([O-])[C]1CCCCCC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TRIM24 O15164 2/20 0.35
TRIM33 Q9UPN9 2/20 0.35
MAPT P10636 3/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4691842 1.00
SCHEMBL498638 0.97
SCHEMBL1742743 0.90
SCHEMBL498154 0.83
SCHEMBL10745831 0.71 TRIM24 (0.32) ALDH1A1TRIM24TRIM33
SCHEMBL19928385 0.69 MAPT (0.35) ALDH1A1MAPTCYP1A2CYP2C19KDM4E
SCHEMBL1170651 0.69 MAPT (0.35) ALDH1A1MAPTCYP1A2CYP2C19KDM4E
SCHEMBL11803198 0.69 MAPT (0.35) ALDH1A1MAPTCYP1A2CYP2C19KDM4E
SCHEMBL31570122 0.69 MAPT (0.35) ALDH1A1MAPTCYP1A2CYP2C19KDM4E
SCHEMBL1170650 0.69 MAPT (0.35) ALDH1A1MAPTCYP1A2CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106398008-A Elastomeric nanocomposite manufacturing 埃克森美孚化学专利公司 2017-02-15 CN disclosed
US-4086341-A NITRO SUBSTITUTED; ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1978-04-25 US disclosed
US-4029806-A Nitro-β-lactam antibiotics and processes for their preparation and use BAYER AKTIENGESELLSCHAFT (DT) 1977-06-14 US disclosed
US-4012518-A PENICILLIN DERIVATIVES AS GROWTH AND FEED UTILIZATION PROMOTERS IN ANIMALS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-15 US disclosed