Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170651 | 1.00 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11803198 | 1.00 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31570122 | 1.00 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11803203 | 1.00 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11803215 | 1.00 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1170650 | 1.00 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL458470 | 0.98 | — | — | |
| Ammonia Solution, Strong SCHEMBL8917963 | 0.95 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1697297 | 0.91 | — | — | |
| SCHEMBL18007273 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10398676-B2 | Use of alpha-hydroxy carbonyl compounds as reducing agents | MORVUS TECHNOLOGY LIMITED (GB) | 2019-09-03 | — | — | US | disclosed |
| US-20180140575-A1 | USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS | GORDIAN PHARMA LIMITED (GB) | 2018-05-24 | — | — | US | disclosed |
| US-9907784-B2 | Use of alpha-hydroxy carbonyl compounds as reducing agents | MORVUS TECHNOLOGY LIMITED (GB) | 2018-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10398676-B2 | Use of alpha-hydroxy carbonyl compounds as reducing agents | DERA, HOGA1, ALDOA | MAPT 3157/4885NPC1 4198/4885RAB9A 4745/4885 |
| US-20180140575-A1 | USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS | DERA, HOGA1, ALDOA | MAPT 3157/4885NPC1 4198/4885RAB9A 4745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.