SCHEMBL11623917

SCHEMBL11623917

NCCCCCNS(=O)(=O)c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.82
KDM4E B2RXH2 2/20 0.82
PKM P14618 2/20 0.82
LMNA P02545 1/20 0.82
SMN1; SMN2 Q16637 1/20 0.82
TBXA2R P21731 1/20 0.66
CYP3A4 P08684 6/20 0.59
CYP1A2 P05177 5/20 0.59
CYP2C9 P11712 5/20 0.59
CYP2C19 P33261 5/20 0.59
SCN1A P35498 2/20 0.59
SCN2A Q99250 2/20 0.59
SCN3A Q9NY46 2/20 0.59
HSD17B10 Q99714 1/20 0.59
MAPK1 P28482 2/20 0.58
HDAC3 O15379 1/20 0.58
HDAC1 Q13547 1/20 0.58
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
CYP2D6 P10635 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11649813 1.00 ALDH1A1 (0.82) ALDH1A1KDM4EPKMLMNASMN1; SMN2
SCHEMBL11807867 1.00 ALDH1A1 (0.82) ALDH1A1KDM4EPKMLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL11628667 0.98 ALDH1A1 (0.79) ALDH1A1KDM4EPKMLMNASMN1; SMN2
SCHEMBL6671584 0.98 ALDH1A1 (0.79) ALDH1A1KDM4EPKMLMNASMN1; SMN2
SCHEMBL6437093 0.93 ALDH1A1 (0.75) ALDH1A1KDM4EPKMLMNASMN1; SMN2
Malonic Acid SCHEMBL7679925 0.92 ALDH1A1 (0.70) ALDH1A1KDM4EPKMLMNASMN1; SMN2
SCHEMBL17787861 0.91 ALDH1A1 (0.68) ALDH1A1KDM4EPKMLMNASMN1; SMN2
SCHEMBL12672471 0.91 ALDH1A1 (1.00) ALDH1A1KDM4EPKMLMNASMN1; SMN2
SCHEMBL21048464 0.91 ALDH1A1 (1.00) ALDH1A1KDM4EPKMLMNASMN1; SMN2
SCHEMBL9577143 0.91 ALDH1A1 (1.00) ALDH1A1KDM4EPKMLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4069254-A INHIBITORS OF BLOOD PLATELET AGGREGATION BANYU PHARMACEUTICAL CO., LTD. (JA) 1978-01-17 US disclosed