⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952345 | 0.72 | — | — | |
| SCHEMBL22692592 | 0.63 | — | — | |
| SCHEMBL21859351 | 0.63 | — | — | |
| SCHEMBL21859417 | 0.60 | INMT (0.56) | — | |
| SCHEMBL21859352 | 0.59 | — | — | |
| SCHEMBL24044988 | 0.58 | — | — | |
| SCHEMBL21676093 | 0.50 | — | — | |
| SCHEMBL11755346 | 0.47 | INMT (0.39) | — | |
| Hydrazine SCHEMBL23924898 | 0.42 | — | — | |
| Hydrazine SCHEMBL3236675 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091105-A | 2-Imino-3-aminothiazolidines and indoleamine-N-methyltransferase inhibition | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4091105-A | 2-Imino-3-aminothiazolidines and indoleamine-N-methyltransferase inhibition | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4091105-A | 2-Imino-3-aminothiazolidines and indoleamine-N-methyltransferase inhibition | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |