Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290934 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL37382 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL30001820 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27144 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL78553 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL9998884 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| Hydrogen Sulfide SCHEMBL2021838 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| Water SCHEMBL8217832 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL30022811 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11630242 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230256413-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES | WATERS TECHNOLOGIES CORPORATION (US) | 2023-08-17 | — | — | US | disclosed |
| EP-4129466-A1 | HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | Waters Technologies Corporation (US) | 2023-02-08 | — | — | EP | disclosed |
| US-20210220753-A1 | HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | WATERS TECHNOLOGIES CORPORATION (US) | 2021-07-22 | — | — | US | disclosed |
| US-10974167-B2 | High purity chromatographic materials comprising an ionizable modifier | WATERS TECHNOLOGIES CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| EP-2714225-B1 | METHOD OF SEPARATION OF LIPID AND BIOLOGICAL MOLECULAR SPECIES USING HIGH PURITY CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORP (US) | 2020-11-11 | — | — | EP | disclosed |
| US-20200332028-A1 | CHARGED SURFACE REVERSED PHASE CHROMATOGRAPHIC MATERIALS METHOD FOR ANALYSIS OF GLYCANS MODIFIED WITH AMPHIPATHIC, STRONGLY BASIC MOIETIES | WATERS TECHNOLOGIES CORPORATION | 2020-10-22 | — | — | US | disclosed |
| EP-3687652-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES | Waters Technologies Corporation (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20190134604-A1 | POROUS MATERIALS WITH CONTROLLED POROSITY; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS | WATERS TECHNOLOGIES CORPORATION | 2019-05-09 | — | — | US | disclosed |
| US-20190126241-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES | WATERS TECHNOLOGIES CORPORATION | 2019-05-02 | — | — | US | disclosed |
| US-20190091606-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | WATERS TECHNOLOGIES CORPORATION (US) | 2019-03-28 | — | — | US | disclosed |
| US-9588130-B2 | Methods for quantifying polypeptides using mass spectrometry | WATERS TECHNOLOGIES CORPORATION (US) | 2017-03-07 | — | — | US | disclosed |
| WO-2017035361-A1 | DISUBSTITUTED COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |
| US-20150087073-A1 | METHODS FOR QUANTIFYING POLYPEPTIDES USING MASS SPECTROMETRY | WATERS TECHNOLOGIES CORPORATION | 2015-03-26 | — | — | US | disclosed |
| US-20140338429-A1 | METHOD OF SEPARATION OF LIPID AND BIOLOGICAL MOLECULAR SPECIES USING HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | WATERS TECHNOLOGIES CORPORATION (US) | 2014-11-20 | — | — | US | disclosed |
| US-20130319086-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | WATERS TECHNOLOGIES CORPORATION (US) | 2013-12-05 | — | — | US | disclosed |
| WO-2013158277-A1 | METHODS FOR QUANTIFYING POLYPEPTIDES USING MASS SPECTROMETRY | WATERS TECHNOLOGIES CORPORATION (US) | 2013-10-24 | — | — | WO | disclosed |
| WO-2012166916-A1 | METHOD OF SEPARATION OF LIPID AND BIOLOGICAL MOLECULAR SPECIES USING HIGH PURITY CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2012-12-06 | — | — | WO | disclosed |
| US-20120273404-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | WATERS TECHNOLOGIES CORPORATION (US) | 2012-11-01 | — | — | US | disclosed |
| EP-2462188-A1 | HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | Waters Technologies Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017418-A1 | HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | WATERS TECHNOLOGIES CORPORATION (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120273404-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER | SPECC1L, SAMM50, RAB5IF | ALDH1A1 963/4885TDP1 4772/4885MAPK1 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.