Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624845 | 0.74 | CA1 (0.34) | CA1CA2CA4KMT2A | |
| SCHEMBL2075446 | 0.71 | — | — | |
| SCHEMBL25864818 | 0.63 | CA1 (0.38) | CA1CA2CA4KMT2A | |
| SCHEMBL16657572 | 0.63 | — | — | |
| SCHEMBL20547768 | 0.63 | — | — | |
| SCHEMBL2174072 | 0.63 | — | — | |
| SCHEMBL1776809 | 0.61 | — | — | |
| SCHEMBL12602390 | 0.61 | CA1 (0.65) | CA1CA2CA4KMT2ATLR4 | |
| SCHEMBL11621266 | 0.60 | MAPK1 (0.36) | KMT2A | |
| SCHEMBL19420022 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070461-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-01-24 | — | — | US | disclosed |