Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624928 | 1.00 | MAPT (0.66) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL20339063 | 0.86 | MAPT (0.68) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL8330997 | 0.85 | MAPT (0.80) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL29772318 | 0.85 | MAPT (0.66) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL8330993 | 0.85 | MAPT (0.80) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL27746894 | 0.84 | PTGER1 (0.72) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL27746895 | 0.84 | PTGER1 (0.72) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL29772316 | 0.84 | MAPT (0.64) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL9368112 | 0.83 | MAPT (0.63) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL9368102 | 0.83 | MAPT (0.63) | MAPTLMNANPC1RAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085135-A | ANTIULCER | TAISHO PHARMACEUTICAL CO., LTD. (JA) | 1978-04-18 | — | — | US | disclosed |