Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368112 | 1.00 | MAPT (0.63) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL11584287 | 0.91 | PTPN1 (0.60) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL11584290 | 0.91 | PTPN1 (0.60) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL5599785 | 0.84 | ABCG2 (0.59) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL11583551 | 0.84 | LMNA (0.57) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL11583549 | 0.84 | LMNA (0.57) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL7197170 | 0.83 | MAPT (0.62) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL7197164 | 0.83 | MAPT (0.62) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL8330993 | 0.83 | MAPT (0.80) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL8330997 | 0.83 | MAPT (0.80) | MAPTNPC1LMNARAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412803-B1 | Chalcone derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-03-23 | — | — | EP | claimed |
| EP-0412803-A1 | Chalcone derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-02-13 | — | — | EP | claimed |
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |
| US-9290427-B2 | Anti-invasive compounds | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | disclosed |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-08 | — | — | US | disclosed |
| EP-2810198-A1 | ANTI-INVASIVE COMPOUNDS | Universiteit Gent (BE) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013113722-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | MMP3, MMP10, MIF | MAPT 3571/4885NPC1 129/4885LMNA 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.