Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622378 | 0.83 | EPHX1 (0.53) | ALDH1A1MAPTCYP1A2HPGDCYP2C19 | |
| SCHEMBL11623259 | 0.77 | F13A1 (0.45) | ALDH1A1GAAL3MBTL1MAPTMAPK1 | |
| SCHEMBL11633216 | 0.77 | KMT2A (0.42) | ALDH1A1POLBTDP1GAAL3MBTL1 | |
| SCHEMBL11623465 | 0.77 | KMT2A (0.42) | ALDH1A1POLBTDP1GAAL3MBTL1 | |
| SCHEMBL11632728 | 0.73 | ALDH1A1 (0.43) | ALDH1A1POLBTDP1GAAMAPT | |
| SCHEMBL11622435 | 0.73 | ALDH1A1 (0.43) | ALDH1A1POLBTDP1GAAMAPT | |
| SCHEMBL31517140 | 0.70 | EPHX1 (0.65) | ALDH1A1GAAL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL17846598 | 0.70 | FNTA (0.39) | ALDH1A1POLBGAAL3MBTL1MAPT | |
| SCHEMBL28417226 | 0.68 | EPHX1 (0.77) | ALDH1A1L3MBTL1MAPTMAPK1CYP1A2 | |
| SCHEMBL3630523 | 0.68 | ALDH1A1 (0.59) | ALDH1A1POLBTDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127656-A | Method of inhibiting lipogensis with 3-(benzoyl)oxiranecarboxamides | SHELL OIL COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4091221-A | LIPOGENESIS INHIBITORS | SHELL OIL COMPANY (US) | 1978-05-23 | — | — | US | disclosed |