Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FHIT | P49789 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13382296 | 0.79 | KDM4E (0.55) | KDM4ELMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL4553774 | 0.76 | KDM4E (0.56) | KDM4ELMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL16346557 | 0.72 | KDM4E (0.49) | KDM4ELMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL14008452 | 0.71 | KDM4E (0.39) | KDM4ELMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL16571310 | 0.70 | HSD17B2 (0.44) | KDM4ELMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL1412618 | 0.70 | ELANE (0.42) | ALDH1A1HPGDCYP1A2SMN1; SMN2MAPK1 | |
| SCHEMBL23830291 | 0.69 | HSD17B10 (0.56) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL11563324 | 0.69 | TSHR (0.46) | KDM4ELMNAALDH1A1HPGDMAPT | |
| SCHEMBL21410580 | 0.68 | KDM4E (0.45) | KDM4ELMNAALDH1A1HPGDMAPT | |
| SCHEMBL7543209 | 0.68 | ALDH1A1 (0.43) | LMNAALDH1A1HPGDCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119727-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1978-10-10 | — | — | US | disclosed |