Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169758 | 0.71 | MAOA (0.33) | MAOBMAOAALDH1A1TSHRKDM1A | |
| SCHEMBL506118 | 0.70 | MAOB (0.54) | MAOBMAOAALDH1A1OPRL1OPRM1 | |
| SCHEMBL11492101 | 0.67 | MAOA (0.46) | MAOBMAOATRPA1ALDH1A1OPRL1 | |
| SCHEMBL2374698 | 0.65 | MAOA (0.54) | MAOBMAOAOPRL1OPRM1OPRK1 | |
| SCHEMBL2374703 | 0.65 | MAOA (0.54) | MAOBMAOAOPRL1OPRM1OPRK1 | |
| SCHEMBL23343753 | 0.65 | OPRL1 (0.65) | MAOBMAOAOPRL1OPRM1OPRK1 | |
| SCHEMBL8347115 | 0.65 | MAOA (0.54) | MAOBMAOAALDH1A1OPRL1OPRM1 | |
| SCHEMBL8284799 | 0.65 | MAOA (0.54) | MAOBMAOAOPRL1OPRM1OPRK1 | |
| SCHEMBL156160 | 0.65 | MAOA (0.54) | MAOBMAOAALDH1A1OPRL1OPRM1 | |
| SCHEMBL1318340 | 0.65 | MAOA (1.00) | MAOBMAOAOPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093615-A | Cyclic oligomers of N-substituted aziridines | THE DOW CHEMICAL COMPANY (US) | 1978-06-06 | — | — | US | disclosed |