SCHEMBL11628019

SCHEMBL11628019

CC(C)CC(O)(CC(C)C)c1cccnc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 5/20 0.47
CYP19A1 P11511 4/20 0.45
CYP3A4 P08684 5/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP3A5 P20815 2/20 0.43
KCNH2 Q12809 1/20 0.43
LMNA P02545 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18779167 0.86 KCNA5 (0.47) KCNA5CYP19A1CYP3A4CYP1A2CYP2C9
SCHEMBL11630638 0.84 CNR1 (0.48) KCNA5CYP19A1CYP3A4CYP3A5KCNH2
SCHEMBL11665308 0.84 KCNA5 (0.40) KCNA5CYP19A1CYP3A4CYP1A2CYP2C9
SCHEMBL11628293 0.84 CNR1 (0.48) KCNA5CYP19A1CYP3A4CYP3A5KCNH2
SCHEMBL11628626 0.83 KCNA5 (0.45) KCNA5CYP19A1CYP3A4CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL11696128 0.81 KCNA5 (0.44) KCNA5CYP19A1CYP3A4CYP1A2CYP2C9
Bromide SCHEMBL11695984 0.81 KCNA5 (0.44) KCNA5CYP19A1CYP3A4CYP1A2CYP2C9
SCHEMBL22060303 0.80 CYP19A1 (0.47) KCNA5CYP19A1CYP3A4CYP1A2LMNA
SCHEMBL10726733 0.80 CYP19A1 (0.48) CYP19A1CYP3A4CYP3A5
SCHEMBL10518994 0.80 NOTUM (0.44) KCNA5CYP3A4CYP3A5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4116665-A Method of regulating the growth of aquatic weeds with pyridine derivatives ELI LILLY AND COMPANY (US) 1978-09-26 US claimed