SCHEMBL11665308

SCHEMBL11665308

CCC(CC)CCC(O)(CC(C)C)c1cccnc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 7/20 0.40
KCNH2 Q12809 3/20 0.38
CYP3A4 P08684 4/20 0.36
CYP3A5 P20815 2/20 0.36
CYP19A1 P11511 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11628019 0.84 KCNA5 (0.47) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
SCHEMBL11628293 0.81 CNR1 (0.48) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
SCHEMBL11630638 0.81 CNR1 (0.48) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
SCHEMBL11628626 0.81 KCNA5 (0.45) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
Bromide SCHEMBL11695984 0.80 KCNA5 (0.44) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
Hydrochloric Acid SCHEMBL11696128 0.80 KCNA5 (0.44) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
Bromide SCHEMBL11702394 0.76 KCNA5 (0.41) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
SCHEMBL18779167 0.75 KCNA5 (0.47) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
SCHEMBL11631301 0.70 KCNA5 (0.43) KCNA5KCNH2CYP3A4CYP3A5CYP19A1
SCHEMBL11627298 0.70 KCNA5 (0.47) KCNA5KCNH2CYP3A4CYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4116665-A Method of regulating the growth of aquatic weeds with pyridine derivatives ELI LILLY AND COMPANY (US) 1978-09-26 US disclosed