Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628373 | 1.00 | LMNA (0.54) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL11626176 | 0.89 | LMNA (0.56) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL11626178 | 0.89 | LMNA (0.56) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| SCHEMBL11622674 | 0.86 | LMNA (0.57) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| SCHEMBL11622677 | 0.86 | LMNA (0.57) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| SCHEMBL11622308 | 0.85 | LMNA (0.72) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| SCHEMBL11624504 | 0.85 | LMNA (0.58) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| SCHEMBL11624508 | 0.85 | LMNA (0.58) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| SCHEMBL11623915 | 0.85 | LMNA (0.57) | LMNACYP2D6MAPK1HIF1ACYP3A4 | |
| SCHEMBL11622313 | 0.85 | LMNA (0.72) | LMNACYP2D6MAPK1HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125612-A | N-1-(p-Biphenylalkyl)piperazines and their use as anti-inflammatory agents | SCHERING CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |