Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134429 | 0.87 | KMT2A (0.59) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL6749821 | 0.82 | KMT2A (0.53) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL19834321 | 0.80 | GAA (0.54) | KMT2AMEN1ALDH1A1F2CA1 | |
| SCHEMBL1200246 | 0.79 | HPGD (0.63) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL3154729 | 0.78 | ALDH1A1 (0.55) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL11543322 | 0.78 | KMT2A (0.59) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL9195631 | 0.77 | KMT2A (0.63) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL999377 | 0.77 | KMT2A (0.68) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL8014864 | 0.77 | KMT2A (0.68) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL3808442 | 0.76 | CA9 (0.56) | KMT2AMEN1HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069325-A | 3-Carbalkoxyamino-1H-2,1,4-benzothiadiazine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |