Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 14/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PDE6A | P16499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296772 | 0.94 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1PDE5APDE4A | |
| SCHEMBL11628793 | 0.91 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1PDE5AGAA | |
| SCHEMBL8294627 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL11710197 | 0.87 | PDE5A (0.54) | KDM4EALDH1A1PDE5APDE4APDE4B | |
| SCHEMBL11626599 | 0.86 | MEN1 (0.51) | KDM4EALDH1A1PDE5APDE4APDE4B | |
| SCHEMBL11628765 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1PDE5AGAA | |
| SCHEMBL11628488 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL11626631 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1L3MBTL1PDE5AGAA | |
| SCHEMBL11628474 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1PDE5AGAA | |
| SCHEMBL11628709 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1PDE5AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4031093-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |