Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631194 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL11628793 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL11628765 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL8294627 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL9296772 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL11708696 | 0.85 | PDE5A (0.51) | PDE5A | |
| SCHEMBL11628682 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL11629795 | 0.84 | IRAK4 (0.52) | PDE5A | |
| SCHEMBL11628488 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL11626631 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1L3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4031093-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |