Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 15/20 | 0.44 |
| ▸ | MEN1 | O00255 | 14/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.44 |
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360003 | 0.82 | GAA (0.45) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL197214 | 0.82 | GAA (0.45) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL4629898 | 0.82 | GAA (0.45) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL1839853 | 0.81 | GAA (0.44) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL9382432 | 0.81 | POLB (0.44) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL2746299 | 0.80 | GAA (0.43) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Thiophene SCHEMBL10901363 | 0.77 | GAA (0.41) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL8076055 | 0.77 | GAA (0.41) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Formamide SCHEMBL11498345 | 0.77 | GAA (0.41) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL7850183 | 0.75 | ABAT (0.44) | GAAMEN1KMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |