Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 15/20 | 0.45 |
| ▸ | MEN1 | O00255 | 13/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.45 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197214 | 0.84 | GAA (0.45) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL4629898 | 0.84 | GAA (0.45) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL9382432 | 0.82 | POLB (0.44) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL11628829 | 0.82 | GAA (0.44) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL1839853 | 0.79 | GAA (0.44) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL2746299 | 0.78 | GAA (0.43) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Thiophene SCHEMBL10901363 | 0.78 | GAA (0.41) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL8076055 | 0.78 | GAA (0.41) | GAAMEN1KMT2AMAPTHSD17B10 | |
| Formamide SCHEMBL11498345 | 0.78 | GAA (0.41) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL7850183 | 0.77 | ABAT (0.44) | GAAMEN1KMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092409-A | The compound that is used for the treatment of leukotriene-related disease | SMITHKLINE BEECHAM CORP (US) | 1994-09-21 | — | — | CN | disclosed |
| CN-1073431-A | The compound that is used for the treatment of leukotriene-related disease | SMITHRLINE BEECHAM CORP (US) | 1993-06-23 | — | — | CN | disclosed |
| CN-1058015-A | Benzoic acid derivative | SMITHKLINE BEECHAM CORP (US) | 1992-01-22 | — | — | CN | disclosed |