SCHEMBL11629065

SCHEMBL11629065

CN(C)C(=O)Nc1cccc(CC(=O)OC2CCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
FAAH O00519 1/20 0.44
MGLL Q99685 1/20 0.44
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
PNPLA2 Q96AD5 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11630554 0.99 CYP19A1 (0.48) CYP19A1SMN1; SMN2MEN1CYP1A2CYP3A4
SCHEMBL11627422 0.98 CYP19A1 (0.44) CYP19A1SMN1; SMN2MEN1CYP1A2CYP3A4
SCHEMBL11629750 0.91 CYP19A1 (0.51) CYP19A1SMN1; SMN2TP53PNPLA2HDAC6
SCHEMBL11631641 0.82 TP53 (0.51) SMN1; SMN2KMT2ATP53PNPLA2HDAC6
SCHEMBL11629895 0.81 EPHX2 (0.57) SMN1; SMN2MEN1KMT2APOLBRAB9A
SCHEMBL11630843 0.80 EPHX2 (0.60) SMN1; SMN2POLBRAB9A
SCHEMBL11629505 0.79 TP53 (0.48) SMN1; SMN2MEN1MAPTKMT2ATP53
SCHEMBL11627155 0.79 POLB (0.56) SMN1; SMN2TP53POLBRAB9AATM
SCHEMBL11629016 0.78 NPC1 (0.63) SMN1; SMN2POLBRAB9A
SCHEMBL11630421 0.78 EPHX2 (0.50) SMN1; SMN2CYP3A4TP53POLBPNPLA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4067726-A 3-Ureido phenylacetamide herbicides BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed