Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631147 | 0.84 | ATM (0.67) | POLBRAB9AATMSMN1; SMN2USP30 | |
| SCHEMBL11630843 | 0.82 | EPHX2 (0.60) | POLBRAB9ASMN1; SMN2ACKR3 | |
| SCHEMBL11625498 | 0.82 | TP53 (0.54) | TP53 | |
| SCHEMBL11630837 | 0.81 | NPC1 (0.65) | POLBRAB9AATMSMN1; SMN2ABL1 | |
| SCHEMBL11629895 | 0.81 | EPHX2 (0.57) | POLBRAB9ASMN1; SMN2ACKR3 | |
| SCHEMBL11630554 | 0.80 | CYP19A1 (0.48) | POLBRAB9AATMSMN1; SMN2TP53 | |
| SCHEMBL11629016 | 0.80 | NPC1 (0.63) | POLBRAB9ASMN1; SMN2ABL1RIN1 | |
| SCHEMBL11626650 | 0.79 | MAP4K4 (0.57) | RAB9AMAP4K4CCR5 | |
| SCHEMBL19444606 | 0.79 | CCR5 (0.64) | RAB9AMAP4K4SMN1; SMN2TP53CCR5 | |
| SCHEMBL11629065 | 0.79 | CYP19A1 (0.47) | POLBRAB9AATMSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |