Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.33 |
| ▸ | MAOA | P21397 | 6/20 | 0.33 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161308 | 0.83 | KDM4E (0.35) | KDM1AMAOAMAOBKDM4EPKM | |
| SCHEMBL31296415 | 0.76 | CD44 (0.31) | — | |
| SCHEMBL16194290 | 0.76 | HTR2A (0.37) | KDM1AMAOAMAOBKDM4EPKM | |
| SCHEMBL28372565 | 0.75 | GAA (0.30) | HTR2A | |
| SCHEMBL13425231 | 0.72 | KDM4E (0.33) | KDM4EPKM | |
| SCHEMBL9657283 | 0.72 | MEN1 (0.33) | KDM4EPKM | |
| SCHEMBL5159548 | 0.72 | KDM4E (0.34) | KDM4EPKM | |
| SCHEMBL5690482 | 0.72 | — | — | |
| SCHEMBL21385202 | 0.71 | POLB (0.30) | — | |
| SCHEMBL11696235 | 0.71 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129580-A | Resolution of certain asymmetric primary amines using lasalocid | HOFFMANN-LA ROCHE INC. (US) | 1978-12-12 | — | — | US | claimed |
| US-4129580-A | Resolution of certain asymmetric primary amines using lasalocid | HOFFMANN-LA ROCHE INC. (US) | 1978-12-12 | — | — | US | disclosed |