SCHEMBL9657283

SCHEMBL9657283

CCC1(c2ccccc2)CC=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
APEX1 P27695 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
OPRM1 P35372 2/20 0.32
OPRL1 P41146 2/20 0.32
OPRK1 P41145 1/20 0.32
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28038790 0.83 GAA (0.32) KDM4EPKMKIF11
SCHEMBL28209280 0.74 SIGMAR1 (0.37) MEN1KMT2ATDP1OPRM1OPRL1
SCHEMBL29639121 0.73 GPR55 (0.33) MEN1CYP1A2TSHRKMT2ATDP1
SCHEMBL28128148 0.73 HDAC4 (0.32)
SCHEMBL11629152 0.72 KDM1A (0.33) KDM4EPKM
SCHEMBL28341268 0.72 KDM4E (0.38) CYP1A2KMT2AKDM4EPKMKIF11
SCHEMBL30897428 0.72 GAA (0.32) OPRM1KDM4EPKM
SCHEMBL27184896 0.72 GAA (0.32) OPRM1KDM4EPKM
SCHEMBL7059784 0.71
SCHEMBL4885179 0.70 PNMT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62294629-A None JP disclosed
EP-0246506-B1 FLUID COMPOSITION, PROCESS FOR PREPARATION THEREOF AND ITS USE AS AN ELECTRIC INSULATING OIL IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-01-02 EP disclosed
EP-0240814-B1 A WORKING FLUID FOR TRACTION DRIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-11-21 EP disclosed
US-4755317-A Decahydronaphthalene compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-07-05 US disclosed
JP-S62294629-A PRODUCTION OF 1-PHENYL-1-NAPHTHYLETHANE IDEMITSU KOSAN CO LTD 1987-12-22 JP disclosed
EP-0246506-A2 Fluid composition, process for preparation thereof and its use as an electric insulating oil IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-11-25 EP disclosed