Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625604 | 0.84 | NOTUM (0.58) | SMN1; SMN2TDP1NPSR1KMT2ANOTUM | |
| Hydrochloric Acid SCHEMBL11626261 | 0.84 | NOTUM (0.44) | SMN1; SMN2TDP1NPSR1KMT2ANOTUM | |
| SCHEMBL11624556 | 0.81 | KMT2A (0.50) | SMN1; SMN2KMT2ATSHRMAPK1MAPT | |
| Potassium Ion SCHEMBL11628010 | 0.81 | NOTUM (0.54) | SMN1; SMN2TDP1NPSR1KMT2ANOTUM | |
| SCHEMBL11625598 | 0.76 | NOTUM (0.55) | SMN1; SMN2TDP1NPSR1KMT2ANOTUM | |
| SCHEMBL10130651 | 0.76 | NOTUM (0.62) | SMN1; SMN2TDP1NPSR1KMT2ANOTUM | |
| Trolamine SCHEMBL11628401 | 0.76 | NOTUM (0.51) | SMN1; SMN2TDP1NPSR1NOTUMTSHR | |
| Potassium Ion SCHEMBL11628009 | 0.75 | NOTUM (0.54) | SMN1; SMN2TDP1NPSR1KMT2ANOTUM | |
| SCHEMBL11625035 | 0.75 | ALDH1A1 (0.62) | TDP1NPSR1KMT2ANOTUMTSHR | |
| SCHEMBL11629638 | 0.75 | TSHR (0.50) | SMN1; SMN2TDP1NPSR1NOTUMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067988-A | 3-Phenyl-1,2,4-oxadiazole derivatives as antiinflammatory-antitussive agents | LABORATOIRES CASSENNE (FR) | 1978-01-10 | — | — | US | claimed |
| US-4067988-A | 3-Phenyl-1,2,4-oxadiazole derivatives as antiinflammatory-antitussive agents | LABORATOIRES CASSENNE (FR) | 1978-01-10 | — | — | US | disclosed |