Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 12/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370680 | 0.69 | CYP11B1 (0.33) | HSD17B3LMNA | |
| SCHEMBL16284194 | 0.67 | NOTUM (0.60) | NOTUMHSD17B3BAZ2BAVPR1A | |
| SCHEMBL10980677 | 0.67 | NOTUM (0.50) | NOTUMHSD17B3LMNAAVPR1A | |
| SCHEMBL10920943 | 0.62 | NOTUM (0.63) | NOTUMHSD17B3BAZ2B | |
| SCHEMBL8221038 | 0.62 | NOTUM (0.63) | NOTUMHSD17B3BAZ2B | |
| SCHEMBL24439313 | 0.62 | HSD17B3 (0.41) | NOTUMHSD17B3 | |
| SCHEMBL6070128 | 0.62 | AHR (0.37) | TP53 | |
| Acetic Acid SCHEMBL28550221 | 0.61 | SRD5A1 (0.58) | NOTUMHSD17B3BAZ2B | |
| SCHEMBL7107264 | 0.61 | NOTUM (0.35) | NOTUMHSD17B3LMNATSHR | |
| SCHEMBL11068898 | 0.61 | NOTUM (0.59) | NOTUMHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093730-A | Methods of using spermicidal vaginal compositions comprising 1,2-benzisothiazole derivatives | PREPHAR PROSPECTION DE RECHERCHES PHARMACEUTIQUES S.A. (CH) | 1978-06-06 | — | — | US | disclosed |