Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37076 | 0.91 | CA1 (0.33) | AHRHTR2CHTR2AHTR2BMETAP1 | |
| SCHEMBL11516655 | 0.91 | CA1 (0.33) | AHRHTR2CHTR2AHTR2BMETAP1 | |
| SCHEMBL6070528 | 0.85 | CYP1A2 (0.42) | HTTPGR | |
| SCHEMBL11661088 | 0.85 | PGR (0.33) | HTR2CHTR2AHTR2BMETAP1PNMT | |
| SCHEMBL472580 | 0.85 | AHR (0.36) | AHRPNMTCYP19A1 | |
| Anthraquinone SCHEMBL9789080 | 0.81 | MAOA (0.43) | METAP1 | |
| 9,10-Phenanthrenequinone SCHEMBL11210917 | 0.80 | S100A4 (0.49) | METAP1HTT | |
| SCHEMBL15281929 | 0.79 | CHRM2 (0.32) | ADRA2ADRD4HSP90AA1 | |
| SCHEMBL11751062 | 0.79 | HTT (0.39) | AHRHTR2CHTR2AHTR2BHTT | |
| SCHEMBL1155668 | 0.79 | DRD2 (0.35) | AHRMETAP1CMA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126011-B2 | Reacting 2-chlorothiobenzoyl chloride with aromatic compound; drug for psychological disorder therapy; photopolymerization sensitizer | PROM LIMITED (GB) | 2006-10-24 | — | — | US | disclosed |
| EP-1334096-B1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | PROM LTD (GB) | 2004-07-28 | — | — | EP | disclosed |
| US-20030229233-A1 | Process for the preparation of thioxanthones | PROM LIMITED (GB) | 2003-12-11 | — | — | US | disclosed |
| EP-1334096-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | Prom Limited (GB) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040464-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | PROM LIMITED (GB) | 2002-05-23 | — | — | WO | disclosed |
| US-4101558-A | Process for preparing thioxanthones | THE SHERWIN-WILLIAMS COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229233-A1 | Process for the preparation of thioxanthones | TST, TPST2, SULT2A1 | AHR 136/4885HTR2C 202/4885HTR2A 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.