SCHEMBL11630463

SCHEMBL11630463

CCOC(=O)CNC(=O)Cc1cccc(N)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPID Q08752 3/20 0.51
PPIB P23284 1/20 0.51
PPIA P62937 1/20 0.51
PPIG Q13427 1/20 0.51
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HDAC4 P56524 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
GAA P10253 2/20 0.44
GLS O94925 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
PRNP P04156 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20515032 0.87 SMN1; SMN2 (0.49) GAAGLSKDM4EALDH1A1CRHBP
SCHEMBL20515073 0.85 SMN1; SMN2 (0.47) KMT2AGAAGLSKDM4EALDH1A1
SCHEMBL274133 0.84 SMN1; SMN2 (0.46) PPIDPPIBPPIAPPIGKMT2A
SCHEMBL1624525 0.84 PPID (0.50) PPIDL3MBTL1HDAC4HDAC6GAA
SCHEMBL20241752 0.84 GLA (0.53) PPIDHDAC4HDAC6GAAKDM4E
Hydrochloric Acid SCHEMBL274132 0.83 SMN1; SMN2 (0.45) PPIDPPIBPPIAPPIGL3MBTL1
SCHEMBL30385493 0.83 PPID (0.66) PPIDKMT2AMEN1HDAC4HDAC6
SCHEMBL2036271 0.83 PPID (0.71) PPIDPPIBPPIAPPIGKDM4E
SCHEMBL11627613 0.81 GLS (0.50) KMT2AMEN1GLSKDM4EALDH1A1
SCHEMBL6322759 0.81 PPID (0.50) PPIDPPIBPPIAPPIGKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4067726-A 3-Ureido phenylacetamide herbicides BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed