Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631966 | 0.90 | MAPK1 (0.43) | TSHRMAPK1GAAL3MBTL1PPARG | |
| SCHEMBL11629614 | 0.85 | MAPK1 (0.48) | TSHRMAPK1GAAHDAC11ALDH1A1 | |
| SCHEMBL11631270 | 0.85 | MAPK1 (0.45) | TSHRMAPK1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL11630993 | 0.84 | TSHR (0.52) | TSHRMAPK1GAAL3MBTL1AKR1B1 | |
| SCHEMBL11630049 | 0.84 | MAPK1 (0.41) | TSHRMAPK1GAAL3MBTL1PPARG | |
| SCHEMBL11631814 | 0.84 | MAPK1 (0.47) | TSHRMAPK1HDAC11MEN1KMT2A | |
| SCHEMBL8948721 | 0.80 | SLC22A6 (0.35) | TSHRKDM5AKDM4CPHF8SLC22A6 | |
| SCHEMBL11750611 | 0.80 | MAPK1 (0.43) | TSHRMAPK1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL11635946 | 0.80 | MAPK1 (0.41) | TSHRMAPK1GAAL3MBTL1ALDH1A1 | |
| SCHEMBL11630200 | 0.78 | MAPK1 (0.43) | TSHRMAPK1GAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111937-A | IODINATED ANILIC ACIDS | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4031088-A | Iodinated anilic acids | STERLING DRUG INC. (US) | 1977-06-21 | — | — | US | disclosed |