Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631680 | 0.90 | MAPK1 (0.58) | TSHRMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL11629297 | 0.85 | TSHR (0.51) | TSHRMAPK1ALDH1A1HSD17B10HSP90AA1 | |
| SCHEMBL11630987 | 0.84 | TSHR (0.43) | TSHRMAPK1GPR84PPARGPPARD | |
| SCHEMBL30881051 | 0.82 | MAPK1 (0.51) | TSHRMAPK1HDAC11ALDH1A1HSD17B10 | |
| Diatrizoic Acid SCHEMBL8859575 | 0.81 | LMNA (0.55) | TSHRMAPK1GPR84PPARGPPARD | |
| Diatrizoic Acid SCHEMBL9052480 | 0.81 | LMNA (0.55) | TSHRMAPK1GPR84PPARGPPARD | |
| SCHEMBL11630623 | 0.80 | MAPK1 (0.51) | TSHRMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL11635946 | 0.80 | MAPK1 (0.41) | TSHRMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL11632892 | 0.80 | MAPK1 (0.48) | TSHRMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL11632856 | 0.78 | MAPK1 (0.46) | TSHRMAPK1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111937-A | IODINATED ANILIC ACIDS | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4031088-A | Iodinated anilic acids | STERLING DRUG INC. (US) | 1977-06-21 | — | — | US | disclosed |